Article

Lactic acidosis, risk factors and predictive laboratory markers: a nested case control study in South Africa

Published in: South African Family Practice
Volume 56 , issue 1 , 2014 , pages: 63–68

DOI: 10.1080/20786204.2014.10844585

Author(s): CA Luke Discipline of Family Medicine, , MYS Moosa Department of Infectious Disease, , TM Esterhuizen Program of Bio Research Ethics and Medical Law, Division of Public Health Medicine, , SE Knight Discipline of Public Health Medicine, , S Saman Port Shepstone Hospital, , A Ross Discipline of Family Medicine,

Keywords: lactic acidosis , stavudine , antiretroviral , toxicity , human immunodeficiency virus

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Abstract

Background: The incidence of antiretroviral therapy (ART)-induced lactic acidosis and its associated mortality may be reduced by appropriate dosing, risk stratification and early detection.

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