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Autoimmune polyglandular syndrome type 1 in a 12-year-old Ugandan girl
Item type: Journal Article • Journal: Journal of Endocrinology, Metabolism and Diabetes of South Africa • Authors: D Kibirige --- Makerere University College of Health Sciences and Dermatology Unit, Mulago National Referral and Teaching Hospital, Uganda F Kambugu --- Makerere University College of Health Sciences and Endocrine Unit, Mulago National Referral and Teaching Hospital, UgandaAutoimmune polyglandular syndrome type 1 (APS-1), also known as autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy syndrome, is a very rare disorder of childhood. It is mainly characterised by the presence of at least two of the following: chronic mucocutaneous candidiasis, chronic hypoparathyroidism and... -
Rheumatoid arthritis
Item type: Journal Article • Journal: South African Family Practice • Authors: Mahmood Ally --- Department of Internal Medicine, Faculty of Health Sciences, Bridget Hodkinson --- Department of Medicine, Groote Schuur Hospital, Faculty of Health Sciences,Immune-mediated inflammatory disorders include a clinically diverse group of conditions that share similar pathogenic mechanisms. Conditions such as rheumatoid arthritis (RA), psoriasis, spondyloarthropathy, inflammatory bowel disease and connective-tissue disease are characterised by immune dysregulation and chronic inflammation. This review will... -
Coeliac disease
Item type: Journal Article • Journal: South African Family Practice • Authors: J Badenhorst --- Department of Internal Medicine,Coeliac disease is an autoimmune enteropathy triggered by the ingestion of gluten-containing cereals, such as wheat, rye and barley. It is estimated to occur in one per cent of people of European ancestry, and in 0.3% of black Africans. Coeliac... -
Exercise prescription in the management of rheumatoid arthritis
Item type: Journal Article • Journal: South African Family Practice • Authors: K Nolte --- Department of Biokinetics, DC Janse van Rensburg --- Section Sports Medicine, University of Pretoria,Background: Over the last few years, the types of exercises prescribed for patients with rheumatoid arthritis (RA) have changed. There is also increasing knowledge on the physical status and physical activity levels of these patients. This article aims to give... -
Immune reconstitution in human immunodefciency virus-positive patients on highly active antiretroviral therapy at an urban public sector district hospital
Item type: Journal Article • Journal: Southern African Journal of Infectious Diseases • Authors: O S Jimoh --- Department of Family Medicine, Nelson R Mandela School of Medicine, M. Naidoo --- Department of Family Medicine, Nelson R Mandela School of Medicine,Immune reconstitution is measured by circulating CD4 T cells that follows a biphasic pattern. Not everyone who is on highly active antiretroviral therapy (HAART) will attain immune reconstitution at the same rate, or to the same extent. This study aimed... -
Nutritional, immune, micronutrient and health status of HIV-infected children in care centres in Mangaung
Item type: Journal Article • Journal: South African Journal of Clinical Nutrition • Authors: L. Steenkamp --- Nutrition Consultant in Private Practice, A. Dannhauser --- Department of Dietetics and Human Nutrition, South Africa D. Walsh --- General Practitioner, G. Joubert --- Department of Biostatistics, South Africa Fj Veldman --- School of Health Technology, South Africa E. Van der Walt --- Department of Dietetics and Human Nutrition, South Africa C. Cox --- Department of Dietetics and Human Nutrition, South Africa Mk Hendricks --- School of Child and Adolescent Health, South Africa H. Dippenaar --- Department of Family Practice, South AfricaAim: To assess the nutritional, immune, micronutrient and health status of antiretroviral-naïve HIV-infected children. -
Lipid emulsions in parenteral nutrition: does one size fits all?
Item type: Journal Article • Journal: South African Journal of Clinical Nutrition • Authors: A. Laviano --- Department of Clinical Medicine, F. Rossi Fanelli --- Department of Clinical Medicine,Dietary lipids significantly contribute to preserve the efficiency of human metabolism and restore it during disease. Therefore, in the absence of absolute contraindications, it would not appear reasonable to exclude lipid emulsions when prescribing parenteral nutrition (PN). The metabolic role... -
Disseminated fungal infection in an HIV-infected patient due to Aureobasidium pullulans
Item type: Journal Article • Journal: Southern African Journal of Infectious Diseases • Authors: Wesley G. van Hougenhouck-Tulleken --- Division of Rheumatology, Department of Internal Medicine, South Africa Garrison Mathole --- Department of Internal Medicine, South Africa Alan Karstaedt --- Division of Infectious Diseases, Department of Internal Medicine, South Africa Nimmisha Govind --- Division of Rheumatology, Department of Internal Medicine, South Africa Magendhree Moodley --- Department of Clinical Microbiology and Infectious Diseases, National Health Laboratory Service, South Africa Sharona Seetharam --- Department of Clinical Microbiology and Infectious Diseases, National Health Laboratory Service, South Africa Nelesh P. Govender --- National Institute for Communicable Diseases(Centre for Opportunistic, Tropical and Hospital Infections), a division of the National Health Laboratory Service, South Africa Colin N. Menezes --- Division of Infectious Diseases, Department of Internal Medicine, South AfricaIn South Africa, novel fungal pathogens have emerged as an important cause of disease in HIV-infected individuals. The clinical presentation is characteristically prolonged, insidious and the diagnosis elusive, often being made post mortem. We report an HIV-infected individual with a... -
Why defaecate on your doorstep? Investigating an unusual behaviour in Africa’s smallest falcon
Item type: Journal Article • Journal: Ostrich: Journal of African Ornithology • Authors: Billi A Krochuk --- FitzPatrick Institute of African Ornithology, DST-NRF Centre of Excellence, South Africa Diana Bolopo --- FitzPatrick Institute of African Ornithology, DST-NRF Centre of Excellence, South Africa Anthony M Lowney --- FitzPatrick Institute of African Ornithology, DST-NRF Centre of Excellence, South Africa Paul R Meyers --- Department of Molecular and Cell Biology, South Africa Claire N Spottiswoode --- FitzPatrick Institute of African Ornithology, DST-NRF Centre of Excellence, South Africa Rajendra MG Raman --- Department of Zoology, UK Robert L Thomson --- FitzPatrick Institute of African Ornithology, DST-NRF Centre of Excellence, South AfricaDepositing faeces at the nest should be expected to carry risks such as increased parasite loads and disease exposure. This perplexing behaviour is unusual in birds but is consistently shown by a handful of species, and has been demonstrated to... -
Prevalence and clinical relevance of thyroid autoantibodies in patients with goitre in Nigeria
Item type: Journal Article • Journal: Journal of Endocrinology, Metabolism and Diabetes of South Africa • Authors: OA Ojo --- Department of Medicine, Nigeria RT Ikem --- Department of Medicine, Nigeria BA Kolawole --- Department of Medicine, Nigeria OE Ojo --- Department of Medicine, Nigeria MO Ajala --- Department of Chemical Pathology, Lagos State Laboratory Services,Background: Thyroid autoimmunity was thought to be rare in Africans but there is evidence that its prevalence is increasing. Since undetected autoimmune thyroid disease carries considerable morbidity, this study set out to determine the proportion of patients with goitre who... -
Effect of nutrition education on nutritional status and serum zinc level of HIV and AIDS clients: implication for care in resource-limited settings
Item type: Journal Article • Journal: African Journal of AIDS Research • Authors: Ifeyinwa Ezenwosu --- , Nigeria Osita Ezenwosu --- , Nigeria Chinyere Mbachu --- , Nigeria Ijeoma Itanyi --- , Nigeria Emmanuel Aguwa --- , NigeriaBackground: People living with HIV or AIDS in resource-limited settings are faced with challenges in their nutrition and micronutrient levels. This study aimed to determine the effect of nutrition education on the nutrition status and serum zinc level of HIV... -
An assessment of sex work in Swaziland: barriers to and opportunities for HIV prevention among sex workers
Item type: Journal Article • Journal: SAHARA-J: Journal of Social Aspects of HIV/AIDS • Authors: Shalote Chipamaunga --- Faculty of Health Sciences, Centre for Health Science Education, University of the Witwatersrand, Adamson S Muula --- University of Malawi College of Medicine, Ronald Mataya --- Loma Linda University School of Public Health, USAThe HIV situation in virtually all southern African countries is a generalised epidemic. Despite the fact that almost all adult age and social groups have high HIV prevalence estimates, sex workers are disproportionally affected, with prevalence estimates higher than the... -
Influence of the home environment on the prevention of mother to child transmission of human immunodeficiency virus/acquired immune-deficiency syndrome in South Africa
Item type: Journal Article • Journal: SAHARA-J: Journal of Social Aspects of HIV/AIDS • Authors: A. Sewnunan --- , , South Africa L.M. Modiba --- , , South AfricaThe human immunodeficiency virus and acquired immune-deficiency syndrome (HIV/AIDS) is still a ‘family crises’ which marks the beginning of the deterioration of the family unit and the trauma in the emotional, psychological and material lives of both the mother and... -
A qualitative evaluation of a stress management programme for HIV and AIDS home-based care workers in Tshwane, South Africa
Item type: Journal Article • Journal: SAHARA-J: Journal of Social Aspects of HIV/AIDS • Authors: P. M. Kupa --- Department of Social Work & Criminology, University of Pretoria, South Africa L. S. Geyer --- Department of Social Work & Criminology, University of Pretoria, South AfricaThe HIV and AIDS pandemic resulted in increased demands on the South African healthcare system and contributed to elevated stress levels among healthcare workers, including home-based care workers. The goal of the study was to evaluate a stress management programme... -
Features of Turner syndrome in patients managed at the adult endocrinology clinic, Steve Biko Academic Hospital
Item type: Journal Article • Journal: Journal of Endocrinology, Metabolism and Diabetes of South Africa • Authors: M. Noeth --- University of Pretoria, South Africa T. Kemp --- University of Pretoria, South Africa T. Botha --- University of Pretoria, South Africa -
Efficacy of immunosuppression in preserving beta cell function and reducing insulin requirements in Type 1 diabetes mellitus: a comprehensive review
Item type: Journal Article • Journal: Journal of Endocrinology, Metabolism and Diabetes of South Africa • Authors: S Pillay --- University of KwaZulu-Natal, South Africa A Pillay --- DRAM Consulting, South Africa A Kalhan --- Royal Glamorgan Hospital, UK
