Review Article

Rheumatoid arthritis

Published in: South African Family Practice
Volume 56 , issue 3 , 2014 , pages: 166–171

DOI: 10.1080/20786204.2014.932547

Author(s): Mahmood Ally Department of Internal Medicine, Faculty of Health Sciences, , Bridget Hodkinson Department of Medicine, Groote Schuur Hospital, Faculty of Health Sciences,

Keywords: immune , inflammatory , rheumatoid arthritis , therapy

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Abstract

Immune-mediated inflammatory disorders include a clinically diverse group of conditions that share similar pathogenic mechanisms. Conditions such as rheumatoid arthritis (RA), psoriasis, spondyloarthropathy, inflammatory bowel disease and connective-tissue disease are characterised by immune dysregulation and chronic inflammation. This review will focus on immunopathogenic mechanisms, aspects of early disease, co-morbidity and therapy in RA.

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