Research Article

Motivating people living with HIV to initiate antiretroviral treatment outside national guidelines in three clinics in the HPTN 071 (PopART) trial, South Africa

Published in: African Journal of AIDS Research
Volume 20 , issue 1 , 2021 , pages: 32–41

DOI: 10.2989/16085906.2020.1854795

Author(s): Constance Mubekapi-Musadaidzwa , South Africa , Dillon Wademan , South Africa , Neshaan Peton , South Africa , Portia Hendricks , South Africa , Gabriela Carolus , South Africa , Rheiner Mbaezue , South Africa , Karen F Kelley , South Africa , James Kruger , South Africa , Karen Jennings , South Africa , Nelis Grobbelaar , South Africa , Francoise Louis , South Africa , Nulda Beyers , South Africa , Helen Ayles , Zambia , Sarah Fidler , UK , Richard Hayes , UK , Peter Bock , South Africa , Graeme Hoddinott , South Africa

Keywords: ART initiation , immediate ART , treatment as prevention , universal testing and treatment (UTT)

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Abstract

Background: The HPTN 071 (PopART) trial implemented universal test and treat (UTT) in three clinics in the Western Cape, South Africa at a time when antiretroviral treatment (ART) was only offered by CD4 threshold and World Health Organization clinical staging. This required a concomitant shift in the way health workers communicated ART initiation messages. We provide insight into front-line ART initiation communication pre-national policy shift.

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