Article

An observational study on factors influencing antibiotic use in chronic obstructive pulmonary disease at Universitas Academic Hospital, Bloemfontein

Published in: South African Family Practice
Volume 57 , issue 4 , 2015 , pages: 273–276

DOI: 10.1080/20786190.2015.1047144

Author(s): Y Dreyer Faculty of Health Sciences, School of Medicine, South Africa , A Rossouw Faculty of Health Sciences, School of Medicine, South Africa , H Schoeman Faculty of Health Sciences, School of Medicine, South Africa , A Van der Nest Faculty of Health Sciences, School of Medicine, South Africa , C Van Zyl Faculty of Health Sciences, School of Medicine, South Africa , M Prins Faculty of Health Sciences, Pulmonology Division, Department of Internal Medicine, South Africa , SD Maasdorp Faculty of Health Sciences, Pulmonology Division, Department of Internal Medicine, South Africa , G Joubert Faculty of Health Sciences, Department of Biostatistics, South Africa

Keywords: acute exacerbation , antibiotic use , C-reactive protein , chronic obstructive pulmonary disease , COPD , CRP

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Abstract

Background: Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are often precipitated by excessive airway inflammation caused by viral or bacterial infections. Current guidelines suggest prescribing antibiotics to patients with AECOPD and purulent sputum production, but this may lead to unnecessary or inappropriate antibiotic use. The aim of this study was to identify clinical and laboratory variables influencing antibiotic prescriptions of clinicians managing patients hospitalised for AECOPD.

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