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Water — The common element: Lessons from antiquity and the health of the environment
Item type: Journal Article • Journal: African Journal of Aquatic Science • Authors: C DickensThe chief pursuit of all aquatic science is to come to know the rules that govern aquatic systems. In this pursuit many scientists move in the direction of greater diversity, where the laws that govern ecosystem relationships become increasingly confined... -
Prevalence of carbapenem resistance genes in Acinetobacter baumannii isolated from clinical specimens obtained from an academic hospital in South Africa
Item type: Journal Article • Journal: Southern African Journal of Epidemiology and Infection • Authors: M.M. Kock --- , A.N. Bellomo --- , N. Storm --- , M.M. Ehlers --- ,Acinetobacter baumannii is an important cause of hospital-acquired infections. The occurrence of carbapenem resistance that is caused by the carbapenem-hydrolysing class Dβ-lactamases and the metallo-β-lactamases (MBLs) limits the range of therapeutic alternatives in treating A. baumannii infections. In this study,... -
NDM-1, novel TEM-205, novel TEM-213 and other extended-spectrum β-lactamases co-expressed in isolates from cystic fibrosis patients from South Africa
Item type: Journal Article • Journal: Southern African Journal of Infectious Diseases • Authors: Nonhlanhla Mhlongo --- Antimicrobial Research Unit, South Africa Sabiha Essack --- Antimicrobial Research Unit, South Africa Usha Govinden --- Antimicrobial Research Unit, South AfricaBackground: β-lactamase-mediated resistance was investigated in isolates from cystic fibrosis (CF) patients attending clinics in the public and private health sectors in Durban, South Africa. -
Horizontal transfer of OXA-23-carbapenemase-producing Acinetobacter species in intensive care units at an academic complex hospital, Durban, KwaZulu-Natal, South Africa
Item type: Journal Article • Journal: Southern African Journal of Infectious Diseases • Authors: Khine Swe Swe-Han --- Department of Medical Microbiology, South Africa Melendhran Pillay --- Department of Medical Microbiology, South Africa Desmond Schnugh --- Infection Control Services Laboratory, Department of Clinical Microbiology and Infectious Diseases, South Africa Koleka P Mlisana --- Department of Medical Microbiology, South Africa Kamaldeen Baba --- Department of Medical Microbiology, National Health Laboratory Service, South Africa Manormoney Pillay --- Medical Microbiology and Infection Control, School of Laboratory Medicine & Medical Science, South AfricaIntroduction: Carbapenemase production is an important mechanism of carbapenem resistance in Acinetobacter species. This study investigated the presence of the carbapenem-hydrolysing class D β–lactamase- encoding genes, blaOXA-23 and blaOXA-58, and their association with the spread of multidrug-resistant (MDR) Acinetobacter species...