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Ectopic ACTH syndrome: a clinical challenge
Item type: Journal Article • Journal: Journal of Endocrinology, Metabolism and Diabetes of South Africa • Authors: NI Tsabedze --- Department of Medicine, Division of Endocrinology and Metabolism, C Ray --- Division of Anatomical Pathology, M Hale --- Division of Anatomical Pathology,A patient was managed in our endocrinology unit with ectopic Cushing's syndrome from an adrenocorticotropic hormone-producing neuroendocrine carcinoma of the anal canal. There was limited response to standard therapy, which made it difficult to correct the electrolyte and metabolic derangements... -
Disseminated large cell neuroendocrine carcinoma associated with ectopic adrenocorticotropic hormone secretion
Item type: Journal Article • Journal: Journal of Endocrinology, Metabolism and Diabetes of South Africa • Authors: A Van der Walt --- Department of Internal Medicine, Division of Endocrinology, K Huddle --- Department of Internal Medicine, Division of Endocrinology, S Pather --- Department of Anatomical Pathology, A Korb --- Department of Internal Medicine Division of Endocrinology, -
Chronic inflammatory demyelinating polyneuropathy, diagnosed as a paraneoplastic manifestation of small cell neuroendocrine carcinoma of the cervix
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: B Chakrabarti --- Department of Radiotherapy, India S Roy --- Department of Radiotherapy, India C Mallik --- Department of Radiotherapy, India K S Bhattacharya --- Department of Radiotherapy, India S Mukherjee --- Department of Radiotherapy, IndiaParaneoplastic syndrome frequently presents before cancer is diagnosed and can be associated with neoplastic disease that is not yet radiographically detectable. We report on the case of a 35-year-old woman who presented at the neurology department with complaints of insidious... -
Advanced neuroendocrine carcinoma (Merkel cell carcinoma) of the vulva: a case report and literature review
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: Adam R Botha --- , South Africa Langanani Mbodi --- , South Africa Reubina Wadee --- , South AfricaNeuroendocrine carcinomas (Merkel cell carcinomas) of the vulva are extremely rare tumours, with very few cases reported to date. Herein, a primary neuroendocrine carcinoma (Merkel cell carcinoma) of the vulva is reported. A 34-year-old HIV-positive female on antiretroviral therapy presented... -
Necrotising migratory erythema leading to the diagnosis of a metastatic glucagonoma without diabetes
Item type: Journal Article • Journal: Journal of Endocrinology, Metabolism and Diabetes of South Africa • Authors: Rahm Makan --- , South Africa Cloete Van Vuuren --- , South AfricaA case of necrotising migratory erythema (NME), which is one of the distinctive paraneoplastic skin manifestations associated with the glucagonoma syndrome, is described and discussed. In 80% of all patients with glucagonoma, NME is the first clinical sign. The glucagonoma... -
Primary ovarian neuroendocrine tumour arising in a benign mature cystic teratoma: a case report and literature review
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: Reubina Wadee --- , South Africa Ian Beavon --- , South Africa Trudy Smith --- , Langanani Mbodi --- ,Primary ovarian neuroendocrine tumours are very uncommon tumours. Herein, we describe a case of 27-year-old female who presented with abdominal pain and an ovarian mass, for which she underwent a right salpingo-oophorectomy. Histopathological evaluation confirmed a right-sided primary ovarian neuroendocrine... -
Nutritional management of a patient with a small bowel neuroendocrine tumour and obstruction: a South African case study
Item type: Journal Article • Journal: South African Journal of Clinical Nutrition • Authors: Kirsten E Drake --- Groote Schuur Hospital, South AfricaSmall bowel neuroendocrine tumours (SBNETs) arise from enterochromaffin cells, most commonly in the terminal ileum. Functional tumours may secrete hormones, which can lead to carcinoid syndrome, whereas non-functional tumours often present later with symptoms of mechanical obstruction. Malnutrition is common...