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Kinetika van nitrifikasie in gronde van die sentrale besproeiingsgebiede in Suid-Afrika
Item type: Journal Article • Journal: South African Journal of Plant and Soil • Authors: D.J. Laubscher --- Departement van Grondkunde, Republiek van Suid-Afrika C.C. du Preez --- Departement van Grondkunde, Republiek van Suid-AfrikaDie verloop van nitrifikasie is in agt gronde, afkomstig van die sentrale besproeiingsgebiede, gemonitor na toediening van (NH4)2SO4 teen die ekwivalent van 100 kg N ha−1 aan beide die bo- en ondergronde. Tydens inkubasie by 30°C is die NH4 +,... -
A study of the kinetics of the adsorption of phosphorus by selected South African soils
Item type: Journal Article • Journal: South African Journal of Plant and Soil • Authors: P.C. Henry --- , MarieF. Smith --- ,Plots of the decline of the concentration of phosphorus in soil suspensions over time were constructed for 23 selected soils from South Africa and, using non-linear regression analysis, various models were fitted to the time curves, including mechanistic first and... -
Two-step approach to determining some useful phosphorus characteristics of South African soils: a review of work done at the ARC-Institute for Soil, Climate and Water
Item type: Journal Article • Journal: South African Journal of Plant and Soil • Authors: P.C. Henry --- , MarieF. Smith --- ,Work carried out at the ARC-Institute for Soil, Climate and Water on soil phosphorus characteristics was reviewed. Regression functions were established in order to test the correlations between P parameters, single point indices and soil properties. The parameters investigated were... -
Bioaccumulation of cadmium in the ascidian Styela clava (Herdman 1881)
Item type: Journal Article • Journal: African Journal of Marine Science • Authors: A Jiang --- Department of Biochemical Engineering, China Z Yu --- Department of Biochemical Engineering, China CH Wang --- Department of Biochemical Engineering, ChinaThe processes of bioaccumulation and elimination of cadmium by tissues of Styela clava (Herdman 1881) were investigated based on a semi-static two-compartment model. The kinetic parameters (accumulation rate constant k 1, elimination rate constant k 2, bioconcentration factor BCF, biological... -
Safety of pain control with morphine: new (and old) aspects of morphine pharmacokinetics and pharmacodynamics
Item type: Journal Article • Journal: Southern African Journal of Anaesthesia and Analgesia • Authors: JF Coetzee --- Department of Anesthesiology and Critical Care,Background: A 26-year-old, 59 kg female was administered morphine 10 mg during tonsillectomy, and 5 mg in the recovery room. She died 5 hours after the operation. Hypoxic cerebral injury, arising from morphine side-effects, was pronounced the cause of death,... -
Strategies for the Prevention and Containment of Antibiotic Resistance
Item type: Journal Article • Journal: South African Family Practice • Authors: SY Essack --- School of Pharmacy and Pharmacology, University of Kwazulu-Natal,Antibiotic resistance may emerge by antibiotic selection pressure but is perpetuated by diverse risk factors and maintained within environments as a result of poor infection control. Population-specific drug pharmacokinetics and pharmacodynamics also play a role. The WHO, US, UK and... -
A pilot study on the use of amikacin in neonates: Who should be monitored for ototoxicity?
Item type: Journal Article • Journal: Southern African Journal of Infectious Diseases • Authors: Deirdré Engler --- Department of Pharmacy, South Africa Natalie Schellack --- Department of Pharmacy, South Africa Alida Naude --- Discipline of Speech- Language Pathology and Audiology, South Africa Andries Gous --- Department of Pharmacy, South AfricaBackground: Aminoglycosides (AGs) cause irreversible hearing loss. The toxic effects of AGs are dose dependent and correlate with increasing drug serum concentrations. -
A multi-centre, phase IV study to evaluate the steady-state plasma concentration and serum bactericidal activity of a generic teicoplanin preparation
Item type: Journal Article • Journal: Southern African Journal of Infectious Diseases • Authors: Oppel Greeff --- Department of Pharmacology, School of Medicine, Faculty of Health Sciences, South Africa Jacob van Tonder --- Department of Pharmacology, School of Medicine, Faculty of Health Sciences, South Africa Duncan Cromarty --- Department of Pharmacology, School of Medicine, Faculty of Health Sciences, South Africa Warren Lowman --- Department of Clinical Microbiology and Infectious Diseases, School of Pathology, South Africa Piet Becker --- Faculty of Health Sciences, South Africa Margo Nell --- Department of Pharmacology, School of Medicine, Faculty of Health Sciences, South AfricaIntroduction: Teicoplanin is an effective treatment option against methicillin-resistant, Gram-positive bacteria, like Staphylococcus aureus. It is a glycopeptide antibiotic, produced through microbial fermentation, a process resulting in variations in the N-acyl side chain. Concerns that these variations may affect the... -
Manganese adsorption by sediment in Wadi Tafna, Algeria
Item type: Journal Article • Journal: African Journal of Aquatic Science • Authors: N Dali-Youcef --- Department of Ecology and Environment, Algeria B Ouddane --- UFR of Chemistry, France Z Derriche --- Department of Chemistry, AlgeriaThe removal of manganese from aqueous solution by sediment in Wadi Tafna, north-western Algeria, was investigated under batch conditions in 2003. Kinetic data equilibrium removal isotherms were measured at 20 °C. The influence of different experimental parameters, such as contact... -
The influence of the wheat rhizosphere on phosphorus desorption kinetics in calcareous soils amended with municipal sewage sludge
Item type: Journal Article • Journal: South African Journal of Plant and Soil • Authors: Tahereh Raiesi --- Horticultural Science Research Institute, Iran Alireza Hosseinpur --- Department of Soil Science, College of Agriculture, Iran Bijan Moradi --- Horticultural Science Research Institute, IranPlant growth in arid environments is limited by phosphorus (P) availability because of the low concentration of P in the soil solution. In addition, soil processes in the rhizosphere affect the mineral nutrition of plants. Thus, greenhouse and laboratory experiments... -
A practical guide to the interpretation of PK/PD profiles of longer-acting analogue insulins. Part one: The principles of glucose clamp studies
Item type: Journal Article • Journal: Journal of Endocrinology, Metabolism and Diabetes of South Africa • Authors: Oppel BW Greeff --- Department of Pharmacology, South Africa Jacob John van Tonder --- Triclinium Clinical Development (Pty) Ltd, South Africa Kershlin Naidu --- Department of Internal Medicine, South Africa Alicia McMaster --- Sanofi-Aventis South Africa (Pty) Ltd, South Africa Alet van Tonder --- Sanofi-Aventis South Africa (Pty) Ltd, South Africa Rashem Mothilal --- Sanofi-Aventis South Africa (Pty) Ltd, South AfricaGlucose clamp studies are used to determine pharmacokinetics (PK) and pharmacodynamics (PD) of analogue insulins. With the development of longer-acting basal analogue insulins, including glargine 300 (Gla-300) and insulin degludec (IDeg), results from numerous glucose clamp studies are readily available... -
A practical guide to the interpretation of PK/PD profiles of longer-acting analogue insulins. Part two: Insulin degludec vs. insulin glargine U300
Item type: Journal Article • Journal: Journal of Endocrinology, Metabolism and Diabetes of South Africa • Authors: Oppel Bw Greeff --- Department of Pharmacology, South Africa Jacob John van Tonder --- Triclinium Clinical Development (Pty) Ltd, South Africa Kershlin Naidu --- Department of Internal Medicine, South Africa Alicia McMaster --- Sanofi-Aventis South Africa (Pty) Ltd, South Africa Alet van Tonder --- Sanofi-Aventis South Africa (Pty) Ltd, South Africa Rashem Mothilal --- Sanofi-Aventis South Africa (Pty) Ltd, South AfricaGlucose clamp studies form an integral part of the early development of insulin therapies. Data generated in these studies are used to establish pharmacokinetic (PK) and pharmacodynamic (PD) profiles of the agents, but methodological differences confound comparison of results from...