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HPV L1 capsid protein detection in high-risk human papillomavirus-positive cervical smears
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: N Heunis --- Department of Anatomical Pathology – Cytology, A Horton --- Consultant Pathologist and Clinical Virologist, Department of Medical Virology, K L Richter --- Consultant Pathologist and Clinical Virologist, Department of Medical Virology, G Dreyer --- Department of Obstetrics and Gynaecology, M Louw --- Department of Anatomical Pathology,Background: The L1 capsid protein is a viral nuclear protein that encapsidates the human papillomavirus (HPV) DNA to build new infectious particles. Previous studies in immune-competent patients have shown that detectable L1 protein in lowgrade squamous intraepithelial lesion (LSIL) smears...
