Article

Acute changes in haematocrit leading to polycythaemia in late-onset hypogonadism patients that receive testosterone replacement therapy: a South African study

Published in: Journal of Endocrinology, Metabolism and Diabetes of South Africa
Volume 24 , issue 2 , 2019 , pages: 37–40

DOI: 10.1080/16089677.2018.1553344

Author(s): Jesslee du Plessis Medicine Usage in South Africa (MUSA), North-West University, South Africa , Hermanus Lambertus Bester Private Hospital, Emalahleni, South Africa, , Marlene Julyan Medicine Usage in South Africa (MUSA), North-West University, South Africa , Marike Cockeran School for Computer, Statistical and Mathematical Sciences, North-West University, South Africa

Keywords: depot-testosterone haematocrit , late-onset hypogonadism , polycythaemia , testosterone replacement therapy , undecanoate

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Abstract

Background: According to the literature, parenteral testosterone replacement therapy (TRT)-induced polycythaemia is associated with cardiovascular events. No or minimal data exist for the prevalence of TRT-induced polycythaemia in late-onset hypogonadism (LOH) patients from South Africa. Polycythaemia is the side effect most frequently associated with parental TRT formulations.

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