Article

Antimicrobial susceptibility of Mycoplasma genitalium isolates from Pretoria, South Africa in 2012 and 2016

Published in: Southern African Journal of Infectious Diseases
Volume 33 , issue 2 , 2018 , pages: 46–49

DOI: 10.1080/23120053.2017.1391505

Author(s): Marie C Le Roux Department of Microbiological Pathology, South Africa , Maanda Mafunise Department of Microbiological Pathology, South Africa , Barbara E de Villiers Department of Microbiological Pathology, South Africa , Ramalau Mm Ditsele Department of Microbiological Pathology, South Africa

Keywords: fluoroquinolone resistance , macrolide resistance , Mycoplasma genitalium , South Africa , termination of pregnancy clinic

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Abstract

Background: Mycoplasma genitalium is a sexually transmitted pathogen associated with non-gonococcal urethritis and cervicitis. Azithromycin regimens have been considered first-line treatment for M. genitalium infections, with fluoroquinolone regimens effective as second-line treatments. However, the proportion of M. genitalium harbouring macrolide or fluoroquinolone resistance-associated mutations has been increasing worldwide. This study was done to compare the genotypic macrolide and fluoroquinolone resistance of M. genitalium strains obtained from women attending a termination of pregnancy clinic five years apart.

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