Microbiological evaluation and antimicrobial treatment of complicated intra-abdominal infections

DOI: 10.1080/10158782.2012.11441484
Author(s): Helen van der PlasDivision Infectious Diseases and HIV Medicine, Department of Medicine,


Intra-abdominal infection is a major cause of morbidity and mortality. The principles of management of intra-abdominal infections include adequate surgical procedures, as well as antimicrobial therapy. This review provides insights into the microbiology of complicated intra-abdominal infections and offers an approach to the microbiological evaluation, as well as antimicrobial treatment strategies, in the South African context. Local antibiotic guidelines for the management of intra-abdominal infections are urgently required to optimise clinical outcomes, while limiting the emergence of resistance, toxicity and the selection of pathogenic organisms.

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