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Human papillomavirus DNA testing on self-collected vaginal tampon samples as a cervical cancer screening test in a Gauteng population

Published in: Southern African Journal of Gynaecological Oncology
Volume 5 , issue sup1 , 2013 , pages: S15–S20

DOI: 10.1080/20742835.2013.11441217

Author(s): E F Mnisi Gynaecological Oncology Unit, Department of Obstetrics and Gynaecology, , G Dreyer Gynaecological Oncology Unit, Department of Obstetrics and Gynaecology, , K L Richter Department of Medical Virology, University of Pretoria; Tshwane Academic Division, , A Horton Department of Anatomical Pathology, University of Pretoria; Tshwane Academic Division, , L C Snyman Gynaecological Oncology Unit, Department of Obstetrics and Gynaecology,

Keywords: cervical cancer screening test , tampon samples , HPV DNA testing , Gauteng population

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Abstract

Background: There is a need to simplify cervical cancer screening to reach more women. Tampon-collected specimens can be tested using molecular methods, but this type of self-screening has not been properly evaluated as a screening method in South Africa before. The objective of this study was to evaluate human papillomavirus (HPV) DNA testing of self-collected tampons as a screening method in an urban and peri-urban population in Gauteng by comparing the results with the current standard of conventional cytology. In addition, HPV prevalence, type, distribution and incidence of cytological abnormalities in this population are described.

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