Antiemetic prophylaxis with promethazine or ondansetron in major gynaecological surgery

Article

Antiemetic prophylaxis with promethazine or ondansetron in major gynaecological surgery

DOI: 10.1080/22201173.2008.10872575
Author(s): OJ Olatosi Department of Anaesthesia, , O Kushimo Department of Anaesthesia, , C Okeke Department of Anaesthesia, , O Oriyomi Shell Hospital, Nigeria , GO Ajayi Department of Obstetrics and Gynaecology,

Abstract

Background: Postoperative nausea and vomiting remain a significant cause of morbidity among patients undergoing general anaesthesia. The optimal strategy for prevention, however, remains controversial. This study evaluated the efficacy of ondansetron 8 mg compared with promethazine 25 mg or placebo for the prevention of nausea and vomiting in patients undergoing elective major gynaecological surgery.

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