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A review of the potential role of tumour-promoting compounds produced by Lyngbya majuscula in marine turtle fibropapillomatosis
Item type: Journal Article • Journal: African Journal of Marine Science • Authors: K Arthur G Shaw C Limpus J UdyHarmful algal blooms (HABs) have increased in abundance and severity in recent decades. Whereas the implications for human impacts and intoxication resulting from blooms have been extensively studied, the ecological implications of these microalgae are less well understood. Many HAB... -
Maxillary brown tumour: unusual presentation of parathyroid carcinoma
Item type: Journal Article • Journal: Journal of Endocrinology, Metabolism and Diabetes of South Africa • Authors: T Hannah --- Department of Surgery, United Kingdom JO Jones --- Plymouth Hospitals NHS Trust, Derriford Hospital, United Kingdom JA Akoh --- Department of Surgery, United KingdomThis is a report of a maxillary brown tumour caused by primary hyperparathyroidism (HPT) secondary to parathyroid carcinoma. A 62-year-old man presented with a large swelling in the right maxilla, which caused right-sided nasal obstruction, intermittent bleeding and diplopia. A... -
Double jeopardy: hypoglycaemia and advanced hepatocellular carcinoma
Item type: Journal Article • Journal: Journal of Endocrinology, Metabolism and Diabetes of South Africa • Authors: V Nicolaou --- Division of Endocrinology, Department of Medicine, R Shires --- Division of Endocrinology, KRL Huddle --- Department of Internal Medicine,Nonislet cell tumour-induced hypoglycaemia is an uncommon, but serious complication of malignancy. The aetiopathogenesis is largely as a result of tumoral overproduction of incompletely processed insulin-like growth factor-II. We describe the case of a 30-year-old black male patient who presented... -
Leiomyoma: a rare cause of adrenal incidentaloma
Item type: Journal Article • Journal: Journal of Endocrinology, Metabolism and Diabetes of South Africa • Authors: M Alteer --- Department of Medicine, Endocrine Division, BH Ascott-Evans --- Department of Medicine and Endocrine Division, M Conradie --- Department of Medicine and Endocrine Division,A 40-year-old, treatment-naïve, human immunodeficiency virus- (HIV) positive male was found to have a large right adrenal incidentaloma on ultrasound of the abdomen, which was confirmed on adrenal computed tomography imaging. The laboratory workup excluded functionality of the mass lesion... -
Eyelid problems in general practice
Item type: Journal Article • Journal: South African Family Practice • Authors: D Smit --- Department of Ophthalmology, Faculty of Health Sciences,General practitioners are often confronted with complaints regarding the eyelids. The author presents a number of clinical cases that illustrate common eyelid problems, and provides a discussion of each case to highlight the important features of the condition. Appropriate treatment... -
Disseminated large cell neuroendocrine carcinoma associated with ectopic adrenocorticotropic hormone secretion
Item type: Journal Article • Journal: Journal of Endocrinology, Metabolism and Diabetes of South Africa • Authors: A Van der Walt --- Department of Internal Medicine, Division of Endocrinology, K Huddle --- Department of Internal Medicine, Division of Endocrinology, S Pather --- Department of Anatomical Pathology, A Korb --- Department of Internal Medicine Division of Endocrinology, -
Pathology of gestational trophoblastic neoplasia: a review with recent insights
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: T Slavik --- Anatomical Pathologist, Ampath Pathology Laboratories, South AfricaGestational trophoblastic neoplasia (GTN) refers to a unique and heterogeneous group of conditions demonstrating differentiation towards various components of gestational trophoblast. Variants of hydatidiform mole (HM) are considered benign, whilst choriocarcinoma (CC), placental site trophoblastic tumour (PSTT) and the more... -
A metastatic unclassified trophoblastic tumour with spontaneous bilateral pneumothoraces
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: P Barnardt --- Department of Medical Imaging and Clinical Oncology, L Fourie --- Department of Medical Imaging and Clinical Oncology,Gestational trophoblastic disease (GTD) is a spectrum of diseases associated with pregnancy. Epithelioid trophoblastic tumour (ETT) is a rare neoplastic proliferation of the intermediate trophoblast that can be distinguished from choriocarcinoma. A 35-year-old female presented with persistent vaginal bleeding, raised... -
Sclerosing stromal tumour of the ovary
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: V Fotedar --- Department of Radiotherapy and Oncology Regional Cancer Centre, India M K Gupta --- Department of Radiotherapy and Oncology Regional Cancer Centre, India R K Seam --- Department of Radiotherapy and Oncology Regional Cancer Centre, India A Tiwari --- Department of Radiotherapy and Oncology Regional Cancer Centre, IndiaSclerosing stromal tumours (SSTs) are rare, benign, sex cord stromal tumours of the ovary. They affect women, who complain mainly of menstrual irregularity, in their second and third decades. We report a histologically confirmed case of a 23-year-old woman who... -
The types and treatment outcomes of germ cell tumours of the ovary seen at Groote Schuur Hospital, Cape Town, between 1994 and 2008: a retrospective survey
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: K E A Mohammed --- Division of Radiation Oncology, A L van Wijk --- Division of Radiation Oncology,Objective: This retrospective observational study aims to review patients with malignant ovarian germ cell tumours (MOGCTs) treated at Groote Schuur Hospital over a 15-year period. -
Management with fertility preservation of an ovarian juvenile granulosa cell tumour presenting with retroperitoneal spread and bilateral ureteric obstruction
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: G C Du Toit --- Part-Time Consultant, Unit of Gynaecological Oncology, Tygerberg Hospital, University of Stellenbosch, -
Small biopsy pathology of mass lesions of the endometrial cavity: differential diagnostic considerations
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: P Liptak --- Consultant Anatomical Pathologist, University of Pretoria; National Health Laboratory Service, R J Barnetson --- Consultant Anatomical Pathologist, Lancet Laboratories,Sampling for histological examination is usually part of the work-up for further planning with regard to the management of patients presenting with uterine bleeding. This review, utilising the classification of the World Health Organization, aims to discuss some commonly recurring... -
Epithelioid trophoblastic tumour: a report of two cases
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: MMA Elhassan --- Radiation Oncology Department, Sudan H-T Wu --- Department of Anatomical Pathology, AL Van Wijk --- Department of Radiation Oncology, -
Nutrition in paediatric Crohn’s disease
Item type: Journal Article • Journal: South African Journal of Clinical Nutrition • Authors: O. Goulet --- Department of Pediatric Gastroenterology, Hepatology and Nutrition, FranceInflammatory bowel disease (IBD) such as Crohn’s disease (CD) results from the interaction between an individual’s immune response and precipitant environmental factors, which generate an anomalous chronic inflammatory response in those who are genetically predisposed. Protein-energy malnutrition (PEM) is a... -
Invasive cervical cancer and human immunodeficiency virus (HIV) infection at Tygerberg Academic Hospital in the period 2003–2007: demographics and characteristics
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: Abdiyah Diarra --- Department of Obstetrics & Gynecology, South Africa Hennie Botha --- Department of Obstetrics & Gynecology, Gynecological Oncology Unit, South AfricaBackground: Despite the prevalence of HIV infection in women with pre-invasive and invasive cervical diseases managed at the Gynaecologic Oncology unit of Tygerberg Hospital, there is a lack of local data on the effect HIV/AIDS has on invasive cervical cancer... -
Human immunodeficiency virus-related Epstein-Barr virus-associated smooth muscle tumours: South African experience from Chris Hani Baragwanath Academic Hospital
Item type: Journal Article • Journal: Southern African Journal of Infectious Diseases • Authors: Sugeshnee Pather --- Division of Anatomical Pathology, National Health Laboratory Service, South Africa Rosalind D. Wainwright --- Haematology and Oncology Unit, Department of Paediatrics, South Africa Faieza Sahid --- Division of Infectious Diseases, Department of Internal Medicine, South Africa Thembi Mashele --- Division of Anatomical Pathology, National Health Laboratory Service, South Africa Eunice J. van den Berg --- Division of Anatomical Pathology, National Health Laboratory Service, South Africa Reena D. Mohanlal --- Division of Anatomical Pathology, National Health Laboratory Service, South AfricaBackground: Despite the rampant human immunodeficiency (HIV) epidemic in Africa, there is a paucity of published data of HIV-related Epstein-Barr virus-associated smooth muscle tumours (EBV-SMT) from Africa. -
Primary peritoneal carcinosarcoma arising from the secondary Müllerian system: case report and literature review
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: Rohini Vinayak Kulkarni --- Gynaecological Oncology Resident, India Rani Akhil Bhat --- Senior Consultant and Head of Department, Gynaecological Oncology, India Vibhawari Dhakharia --- Department of Gynaecological Oncology, India Jagannath Dixit --- Department of Surgical Oncology, India Aparna Gangoli --- Department of Pathology, India Kunal Sharma --- Department of Pathology, IndiaCarcinosarcomas, also known as malignant mixed Müllerian tumours (MMMT), are aggressive neoplasms that are biphasic as they contain both carcinomatous and sarcomatous elements. Most commonly arising from the endometrium, extragenital carcinosarcomas are extremely rare and most cases develop from the... -
A retrospective analysis of the effect of planning tumour volume on survival in cervical carcinoma
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: Ilze Fourie --- Division of Radiation Oncology, Stellenbosch University, Tygerberg Academic Hospital, South Africa Hannah M Simonds --- Division of Radiation Oncology, Stellenbosch University, Tygerberg Academic Hospital, South AfricaIntroduction: Locally advanced stages of invasive cervical cancer (ICC) are associated with poor outcomes; factors influencing survival include increased tumour volume. In resource-constrained settings access to diagnostic imaging with CT and MRI is limited. Alternative methods of establishing tumour volume... -
Midgut neuroendocrine tumour presenting as orbital metastases
Item type: Journal Article • Journal: Journal of Endocrinology, Metabolism and Diabetes of South Africa • Authors: Helen Hoenck --- , South Africa Wilhelmina Conradie --- , South Africa Magda Conradie --- , South Africa Ankia Coetzee --- , South AfricaMetastasis of a neuroendocrine tumour (NET) to the orbit is a rare occurrence, with published data limited to a few case reports. Orbital involvement usually presents with proptosis and decreased ocular mobility. Timing, in relation to the presentation of the... -
Primary ovarian neuroendocrine tumour arising in a benign mature cystic teratoma: a case report and literature review
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: Reubina Wadee --- , South Africa Ian Beavon --- , South Africa Trudy Smith --- , Langanani Mbodi --- ,Primary ovarian neuroendocrine tumours are very uncommon tumours. Herein, we describe a case of 27-year-old female who presented with abdominal pain and an ovarian mass, for which she underwent a right salpingo-oophorectomy. Histopathological evaluation confirmed a right-sided primary ovarian neuroendocrine... -
A retrospective study of the epidemiology and histological subtypes of ovarian epithelial neoplasms at Charlotte Maxeke Johannesburg Academic Hospital
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: Lusela Pillay --- , South Africa Reubina Wadee --- , South Africa -
Nutritional management of a patient with a small bowel neuroendocrine tumour and obstruction: a South African case study
Item type: Journal Article • Journal: South African Journal of Clinical Nutrition • Authors: Kirsten E Drake --- Groote Schuur Hospital, South AfricaSmall bowel neuroendocrine tumours (SBNETs) arise from enterochromaffin cells, most commonly in the terminal ileum. Functional tumours may secrete hormones, which can lead to carcinoid syndrome, whereas non-functional tumours often present later with symptoms of mechanical obstruction. Malnutrition is common...