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Radiation therapy for cervix carcinoma: the benefits and constraints in sub-Saharan Africa
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: H M Simonds --- Division of Radiation Oncology, Tygerberg Hospital, South AfricaCervix carcinoma is one of the most prevalent cancers in women in Africa. Primary and secondary prevention measures in place are currently not sufficient to prevent further cases. Radiotherapy is the main therapeutic option as most cases present at a... -
Long-term complications of pelvic radiotherapy
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: H Simonds --- Division of Radiation Oncology Tygerberg Hospital/University of Stellenbosch,Complications following pelvic radiation are frequently under-reported and inadequately addressed. This overview examines the nature and the intensity of complications encountered by cancer survivors; it focuses specifically on gastrointestinal and vaginal complications, and the problems surrounding the methods of recording... -
A pilot study of two radiation fractionation regimens in patients with cancer of the cervix, who were HIV positive and not on antiretroviral therapy
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: A M Hocepied --- Department of Radiation Oncology, H Westerink --- Department of Radiation Oncology, R Lakier --- Department of Radiation Oncology,The Department of Radiation Oncology at the previously named Pretoria Academic Hospital (now the Steve Biko Hospital) undertook a pilot study between 2000 and 2001 of 20 patients who were human immunodeficiency virus-positive with locally advanced cancer of the cervix... -
Pharmacological options for the protection of ovarian function in patients undergoing chemotherapy
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: MH Botha --- Unit for Gynaecological Oncology, Department of Obstetrics and Gynaecology, Faculty of Medicine and Health Sciences,Chemotherapy, particularly alkylating agents, can be toxic to germ cells, and may lead to treatment amenorrhoea in young women. The age at which chemotherapy is administered is a strong predictor of subsequent premature ovarian failure, with older patients being at... -
Retrospective analysis of patients with cancer of the cervix attending a radiotherapy outpatient department: experience from a university-based hospital in eastern Uttar Pradesh, India
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: M Nandi --- Department of Radiation Oncology, India A Mandal --- Department of Radiotherapy and Radiation Medicine, Institute of Medical Sciences, India AK Asthana --- Radiotherapy and Radiation Medicine, Institute of Medical Sciences, IndiaObjective: A retrospective analysis of all patients with cancer of the cervix attending a radiotherapy outpatients department in a single unit from January 2005 to December 2006 was carried out to study their epidemiology, stage and status of presentation, compliance... -
The impact of HIV infection on women receiving radiation for cervical cancer
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: Mapule Mangena --- Gynaecological Oncology Unit, Department of Obstetrics and Gynaecology, Leon Snyman --- Gynaecological Oncology Unit, Department of Obstetrics and Gynaecology, Greta Dreyer --- Gynaecological Oncology Unit, Department of Obstetrics and Gynaecology, Sheynaz Bassa --- Department of Radiation Oncology, Piet Becker --- Research Office, Faculty of Health Sciences,Background: The objective of the study was to compare patient characteristics, treatment toxicity and interruptions, and survival in human immunodeficiency virus (HIV)-positive and HIV-negative cervical cancer patients receiving radiation as primary or adjuvant treatment. -
Cobalt-60 is a logical, economical and comparable alternative to Ir-192: analysis and institutional experience from western India
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: Upendra Nandwana --- Radiotherapy Department, India Narendra Rathore --- Radiotherapy Department, India Sunnia Gupta --- Radiotherapy Department, India Arvind Shukla --- Radiotherapy Department, India Satish Kumar --- Radiotherapy Department, India Kiran Intodia --- Radiotherapy Department, India Poonam Chand Bana --- Radiotherapy Department, India Abhay Jain --- Radiotherapy Department, IndiaObjectives: The objective of the study was to examine the dosimetry of intracavitary radiotherapy (ICRT) in carcinoma of the cervix using cobalt-60 (Co-60) as source of ICRT, and as an alternative to iridium-192 (Ir-192). -
Lymphovascular space invasion in early-stage endometrial cancer: adjuvant treatment and patterns of recurrence
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: Esther van Barneveld --- Department of Obstetrics and Gynaecology, The Netherlands David G Allen --- Department of Obstetrics and Gynaecology, Australia Ruud LM Bekkers --- Department of Obstetrics and Gynaecology, The Netherlands Peter T Grant --- Department of Obstetrics and Gynaecology, AustraliaBackground: In early-stage endometrial cancer, lymphovascular space invasion (LVSI) is an independent predictor of relapse of disease and poorer survival. Nevertheless, adjuvant treatment for LVSI-positive patients is variable. -
Characteristics and outcome of surgically treated acromegaly patients attending an endocrinology clinic at a tertiary referral centre in Durban, South Africa over a period of 10 years
Item type: Journal Article • Journal: Journal of Endocrinology, Metabolism and Diabetes of South Africa • Authors: Abdurraouf Masaud Elbueishi --- Department of Diabetes and Endocrinology, South Africa Fraser J Pirie --- Department of Diabetes and Endocrinology, South Africa Ayesha A Motala --- Department of Diabetes and Endocrinology, South AfricaBackground: The mode of presentation, clinical, radiologic and laboratory characteristics of patients with acromegaly and the outcome following various modalities of treatment are not well documented in South Africa. -
Acute toxicity in cervical cancer HIV-positive vs. HIV-negative patients treated by radical chemo-radiation in Zambia
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: Sibusiso Mdletshe --- Medical Imaging and Radiation Sciences Department, South Africa Harry Munkupa --- Oncology Center, Zambia Kennedy Lishimpi --- Oncology Center, ZambiaBackground: The current standard of radical treatment for patients with cancer of the cervix is combination therapy in the form of radiotherapy with chemotherapy. Generally the same treatment protocol is applied to HIV-positive and HIV-negative patients. However, HIV-positive patients with... -
Retrospective analysis of radiotherapy outcomes in breast cancer radiotherapy at a single institution
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: M Heunis --- Radiation Oncology, South Africa DC Lombe --- Radiation Oncology, South Africa M McCaul --- Biostatistics Unit, Division of Epidemiology and Biostatistics, Department of Global Health, South AfricaIntroduction: Breast cancer is the most commonly diagnosed cancer worldwide. With the challenges of cancer treatment in developing countries there is a need for a systematic and methodical approach to treatment in resource-limited settings. -
A retrospective study of stage IB node-negative cervical cancer treated with adjuvant radiation with standard pelvic versus central small pelvic fields
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: Tlotlo B Ralefala --- Division of Radiation Oncology, South Africa Leon van Wijk --- Division of Radiation Oncology, South Africa Rakiya Saidu --- Department of Obstetrics & Gynaecology, College of Health Sciences, NigeriaObjective: To compare two types of postoperative radiation therapy (PORT) in early-stage, node-negative cervical cancer treated at Groote Schuur Hospital, Cape Town, South Africa. -
A retrospective analysis of the effect of planning tumour volume on survival in cervical carcinoma
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: Ilze Fourie --- Division of Radiation Oncology, Stellenbosch University, Tygerberg Academic Hospital, South Africa Hannah M Simonds --- Division of Radiation Oncology, Stellenbosch University, Tygerberg Academic Hospital, South AfricaIntroduction: Locally advanced stages of invasive cervical cancer (ICC) are associated with poor outcomes; factors influencing survival include increased tumour volume. In resource-constrained settings access to diagnostic imaging with CT and MRI is limited. Alternative methods of establishing tumour volume... -
Bone involvement in patients with cervical carcinoma: a single-institution cohort study
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: JL Butt --- Department of Obstetrics and Gynaecology, Tygerberg Hospital, South Africa MH Botha --- Department of Obstetrics and Gynaecology, Tygerberg Hospital, South AfricaIntroduction: Bony metastases in cervical carcinoma are rare; however, autopsy studies indicate that they are underdiagnosed. A retrospective study was undertaken to describe the risk factors and tumour characteristics and estimate the prevalence of bone involvement in women with cervical... -
A cohort study of treatment outcomes after radiotherapy in vulva carcinoma patients
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: T Goba-Mjwara --- , South Africa H Simonds --- , South Africa