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The usage and efficacy of a combination analgesic preparation
Item type: Journal Article • Journal: Southern African Journal of Anaesthesia and Analgesia • Authors: M Raff --- Pain management unit, South AfricaCombination analgesics are frequently prescribed for the treatment of a multitude of conditions. Many of these preparations contain agents with no proven analgesic efficacy. We examined 3059 patients using a new combination agent containing only paracetamol, codeine, and ibuprofen. It... -
Postoperative analgesia in children: getting it right
Item type: Journal Article • Journal: Southern African Journal of Anaesthesia and Analgesia • Authors: CA Lee --- Department of Anaesthesiology,The management of postoperative pain in children has historically been poor, but advances have been made in the last decade. As pain is a complex phenomenon, a multimodal approach to treatment is required. This article aims to give a brief... -
Effectiveness of tramadol/paracetamol compared with etoricoxib as postoperative analgesia in daycare surgery
Item type: Journal Article • Journal: Southern African Journal of Anaesthesia and Analgesia • Authors: Choy Y. Choy --- Department of Anaesthesiology and Intensive Care, Adnan Isquandar --- Department of Anaesthesiology and Intensive Care,Objective: The objective was to evaluate the effectiveness of a fixed, tramadol/paracetamol combination when compared with etoricoxib as postoperative analgesia following day care surgery. -
A randomised clinical trial comparing the analgesic and anxiolytic efficacy and tolerability of Stilpane® and Tramacet® after third molar extraction
Item type: Journal Article • Journal: Southern African Journal of Anaesthesia and Analgesia • Authors: K Outhoff --- Department of Pharmacology, South Africa JM Dippenaar --- Department of Maxillo Facial Oral Surgery, Oral and Dental Hospital, South Africa M Nell --- Department of Pharmacology, South Africa M Royds --- CyteSpace, South Africa OBW Greeff --- Department of Pharmacology, South AfricaBackground: Successful treatment of moderate to severe acute pain often necessitates several analgesics that target different sites of the nociceptive pathway. Fixed-dose combination analgesics facilitate a reduction in dose of individual components, increased compliance and strong-opioid sparing. The aim of... -
The management of acute pain after gynaecological surgery
Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: P Le Roux --- Principal Specialists, Anaesthesiology and Critical Care, Tygerberg Hospital, M De Kock --- Principal Specialists, Anaesthesiology and Critical Care, Tygerberg Hospital,We have an improved understanding of the pathophysiology and impact of perioperative pain. Targeted interventions to prevent and manage nociception are effective in improving patient satisfaction and surgical outcome. There are many alternatives, each with its own profile of benefits,... -
Intravenous paracetamol — waste not, want not: a retrospective audit on the appropriate use of intravenous paracetamol at Universitas Academic Hospital Complex—Bloemfontein
Item type: Journal Article • Journal: Southern African Journal of Anaesthesia and Analgesia • Authors: NJ Procter --- Department of Anaesthesiology, South Africa G Lamacraft --- Department of Anaesthesiology, South Africa G Joubert --- Department of Biostatistics, South AfricaBackground: Paracetamol can be given both orally and intravenously (IV) with similar clinical efficacy, but the IV formulation is 360 times more expensive. IV paracetamol is therefore only recommended when the oral route is not available. This study investigated whether...