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The epidemiology and pathogenesis of type 1 diabetes mellitus in Africa
Item type: Journal Article • Journal: Journal of Endocrinology, Metabolism and Diabetes of South Africa • Authors: CJ Padoa --- Department of Chemical Pathology National Health Laboratory Service,Type 1 diabetes is a serious, debilitating disease, with life-threatening complications, and the financial burden associated with the management of this disease is enormous. Early diagnosis and intervention can improve morbidity and mortality. Unfortunately, in Africa, type 1 diabetes is... -
Seroprevalence of polio antibodies in adult laboratory staff in South Africa, 2009 to 2013
Item type: Journal Article • Journal: Southern African Journal of Infectious Diseases • Authors: Shelina Moonsamy --- Centre for Vaccines and Immunology, South Africa Melinda Suchard --- Centre for Vaccines and Immunology, South AfricaThe global eradication of polio has been a World Health Organization goal since May 1988 with the current target for global eradication set at 2018. A keystone of the eradication initiative is achieving and maintaining high immunisation coverage, producing high... -
Development of gene expression assays measuring immune responses in the spotted hyena (Crocuta crocuta)
Item type: Journal Article • Journal: African Zoology • Authors: Roxanne L Higgitt --- DST/NRF Centre of Excellence for Biomedical Tuberculosis Research/SAMRC Centre for TB Research/Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, South Africa Peter E Buss --- Veterinary Wildlife Services, South African National Parks, Kruger National Park, South Africa Paul D van Helden --- DST/NRF Centre of Excellence for Biomedical Tuberculosis Research/SAMRC Centre for TB Research/Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, South Africa Michele A Miller --- DST/NRF Centre of Excellence for Biomedical Tuberculosis Research/SAMRC Centre for TB Research/Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, South Africa Sven DC Parsons --- DST/NRF Centre of Excellence for Biomedical Tuberculosis Research/SAMRC Centre for TB Research/Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, South AfricaAs scavengers, spotted hyenas (Crocuta crocuta) are exposed to a wide array of pathogens but exhibit low mortality rates due to infectious disease. This suggests that this species exhibits a unique and robust immune response to pathogens. However, few tools... -
Susceptibility to hepatitis B infection, hepatitis B/HIV co-infections and hepatitis B immunity in HIV-positive patients starting HAART in Durban, South Africa
Item type: Journal Article • Journal: South African Family Practice • Authors: FM Chonco --- Department of Family Medicine, South Africa S Rangiah --- Department of Family Medicine, South AfricaBackground: HIV/HBV co-infection remains a global threat to HIV management despite the available effective hepatitis B vaccine and hepatitis B covering antiretroviral therapy. Many studies done in South Africa and internationally showed high prevalence of HIV/hepatitis B co-infection, which mandated... -
Characterisation, prevalence and antibiogram of Aeromonas hydrophila in turtles: insights into virulence factors, antimicrobial resistance genes and innate immunity
Item type: Journal Article • Journal: African Journal of Herpetology • Authors: Ahmed R. Khafagy --- Suez Canal University, Egypt Atef M. Kamel --- Suez Canal University, Egypt El-sayed N. Abou El Ghait --- National Institute of Oceanography and Fisheries (NIOF), Egypt Nermeen M. Mohamed --- Cairo University, Egypt Nada H. Eidaroos --- Suez Canal University, Egypt Fatma A. Hagag --- National Institute of Oceanography and Fisheries (NIOF), Egypt Mohamed Fathi --- National Institute of Oceanography and Fisheries (NIOF), EgyptBacterial infection poses a significant threat to the health and survival of turtles, both in their natural habitats and in captivity. Notably, the presence and interactions of bacteria, such as those belonging to the Aeromonas genus, have been identified for...