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  1. Dipeptidyl peptidase-4 inhibitors: their role in the management of type 2 diabetes

    Dipeptidyl peptidase-4 inhibitors: their role in the management of type 2 diabetes

    Item type: Journal Article • Journal: South African Family Practice • Authors: Gail Mkele [AN0001]
    The production of glucagon-like peptide 1 (GLP-1), an incretin hormone, has been shown to be abnormally low in patients with type 2 diabetes, suggesting that GLP-1 may be a contributor in the pathogenesis of the disease. New type 2 diabetic...
  2. Dipeptidyl peptidase-4 inhibitors: their role in the management of type 2 diabetes

    Dipeptidyl peptidase-4 inhibitors: their role in the management of type 2 diabetes

    Item type: Journal Article • Journal: Journal of Endocrinology, Metabolism and Diabetes of South Africa • Authors: Gail Mkele [cor1]
    The production of glucagon-like peptide 1 (GLP-1), an incretin hormone, has been shown to be abnormally low in patients with type 2 diabetes, suggesting that GLP-1 may be a contributor in the pathogenesis of the disease. New type 2 diabetic...
  3. Necrotising migratory erythema leading to the diagnosis of a metastatic glucagonoma without diabetes

    Necrotising migratory erythema leading to the diagnosis of a metastatic glucagonoma without diabetes

    Item type: Journal Article • Journal: Journal of Endocrinology, Metabolism and Diabetes of South Africa • Authors: Rahm Makan --- , South Africa Cloete Van Vuuren --- , South Africa
    A case of necrotising migratory erythema (NME), which is one of the distinctive paraneoplastic skin manifestations associated with the glucagonoma syndrome, is described and discussed. In 80% of all patients with glucagonoma, NME is the first clinical sign. The glucagonoma...