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1. 

   Lipid rescue: the use of lipid emulsions to treat local anaesthetic toxicity

   Item type: Journal Article • Journal: Southern African Journal of Anaesthesia and Analgesia • Authors: CJ Kruger --- Department of Anaesthesiology and Critical Care, South Africa PC Marwick --- Department of Anaesthesiology and Critical Care, South Africa AI Levin --- Department of Anaesthesiology and Critical Care, South Africa

   Despite increasing safety of regional anaesthesia, the growth in the popularity therof implies that local anaesthetic toxicity will occur occasionally. Local anaesthetic cardiotoxicity, even when using “safer” modern local anaesthetics, is notoriously resistant to standard resuscitation. The aim of this...

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2. 

   HER-2 positive breast cancer and trastuzumab: lessons learnt by heart

   Item type: Journal Article • Journal: Southern African Journal of Gynaecological Oncology • Authors: K Outhoff --- Department of Pharmacology, South Africa

   Women treated with trastuzumab have an increased risk for developing cardiac problems, particularly if they receive prior or concurrent anthracyclines. Left ventricular dysfunction associated with trastuzumab treatment may progress to severe New York Heart Association (NYHA) class III/IV heart failure...

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