Article

Optimum INR intensity and therapeutic INR control in patients with mechanical heart valve prosthesis on warfarin oral anticoagulation at Dr George Mukhari academic hospital: a three-year retrospective study

Published in: South African Family Practice
Volume 60, issue 6, 2018 , pages: 192–196
DOI: 10.1080/20786190.2018.1467182
Author(s): S NtlokotsiDepartment of Internal Medicine, School of Medicine, South Africa, MF MosheshDepartment of Internal Medicine, School of Medicine, South Africa, P MntlaDepartment of Internal Medicine, School of Medicine, South Africa, OA TowobolaDepartment of Internal Medicine, School of Medicine, South Africa, MA MogaleDepartment of Biochemistry, School of Science & Technology, South Africa

Abstract

Background: Available evidence suggest that the optimum prothrombin time-international normalised ratio (PT-INR) intensities recommended for anticoagulation of patients with mechanical heart valve prosthesis may not apply to all race groups. Optimal PT-INR target ranges and effectiveness of warfarin oral anticoagulation were determined among black South African patients fitted with St Jude bileaflet mechanical heart valve prosthesis (SJBMHVP) at Dr George Mukhari Academic Hospital (DGMAH).

Get new issue alerts for South African Family Practice