Brief Report

Delivery of isoniazid preventive therapy to reduce occupational TB among healthcare workers in Swaziland

DOI: 10.1080/23120053.2016.1181421
Author(s): Marianne CalnanUniversity Research Co., LLC, Swaziland, Samson HaumbaUniversity Research Co., LLC, Swaziland, Makhosazana MatsebulaUniversity Research Co., LLC, Swaziland, Ntombifuthi ShongweUniversity Research Co., LLC, Swaziland, Munyaradzi PasipamireSwaziland National AIDS Program, Swaziland, Natalie Kruse LevyUSAID/PEPFAR, Swaziland, Munamato MiriraUSAID/PEPFAR, Swaziland, Peter PrekoCDC, Swaziland, Alisha Smith-ArthurUniversity Research Co., LLC, USA, Varduhi GhazaryanUniversity Research Co., LLC, USA


Healthcare workers (HCWs) in Swaziland are at increased risk of acquiring tuberculosis (TB), but existing infection control and occupational health policies often fall short of mitigating the risk of acquiring TB in the workplace. Health service failure to systematically offer isoniazid preventive therapy (IPT) to HCWs, which is endorsed by the World Health Organisation (WHO), contributes significantly to the TB incidence among HCWs in high HIV prevalence settings. This paper describes a pilot introduction of IPT to HCWs, and expounds possible determinants for adherence and non-acceptance to IPT. Acceptance to the widespread use of IPT among HCWs can be improved through education on risk and counselling.

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